Chiral Separation Methods for Pharmaceutical and Biotechnological Products

Content:
Chapter 1 Overview of Chiral Separations (pages 1–8): Satinder Ahuja
Chapter 2 Regulatory and Development Considerations of Chiral Compounds (pages 9–34): Robert L. Zeid
Chapter 3 Basic Considerations in HPLC Method Development of Chiral Compounds (pages 35–56): Satinder Ahuja
Chapter 4 Separation of Chiral Compounds on Polysaccharide Columns (pages 57–129): Clinton W. Amoss and Norbert M. Maier
Chapter 5 Chiral Separations by Various Techniques (pages 131–145): Jian G. Ning
Chapter 6 Chiral Discrimination Study for Polysaccharide?Based Chiral Stationary Phases (pages 147–191): Yun K. Ye
Chapter 7 Comparison of Chiral Chromatography Columns for Pharmaceutical Method Development (pages 193–208): Gregory K. Webster
Chapter 8 Chiral Screening Methods for Pharmaceutical Analysis and Purification in an Industrial Laboratory (pages 209–250): Robert DePianta, Kenneth Douville, Beverly Nickerson and Ricardo E. Borjas
Chapter 9 Separation of Enantiomers by Gas Chromatography on Chiral Stationary Phases (pages 251–297): Volker Schurig
Chapter 10 Separations of Chiral Compounds by SFC (pages 299–329): Ziqiang Wang
Chapter 11 Chiral Separations by Capillary Electrophoresis (pages 331–381): Debby Mangelings and Yvan Vander Heyden
Chapter 12 High?Throughput Screening and Method Development Strategies to Separate Chiral Drug Compounds in HPLC, SFC, and CE (pages 383–416): Hasret Ates, Debby Mangelings and Yvan Vander Heyden
Chapter 13 Use of Enantioselective Synthesis and Preparative Chiral Chromatography to Access a Challenging Enantiopure Pharmaceutical Candidate from a Mixture of Four Stereoisomers (pages 417–427): Christopher J. Welch, Derek H. Henderson, William R. Leonard, Mirlinda Biba, Mike Zacuto, Fred Fleitz, Amude Kassim, Cheng?yi Chen and Peter Sajonz
Chapter 14 A Look into the Future: Chiral Analysis Using Chemical Sensor Technology (pages 429–439): Gregory K. Webster and William J. Buttner
Chapter 15 Chirality of Biomolecules and Biotechnology Products (pages 441–467): Satinder Ahuja